The NSS-2 Bridge, a small electrical nerve stimulator placed behind the patient’s ear w/ battery-powered chip that emits electrical pulses to stimulate branches of certain cranial nerves was approved in mid-November by the FDA. Patients can use the device for up to five days during the acute physical withdrawal phase and it is available only as prescription.
The FDA reviewed data from a single-arm clinical study of 73 patients undergoing opioid physical withdrawal. Prior to using the device, the average COWS score for all patients was 20.1. Study results showed that all patients had a reduction in COWS of at least 31 percent within 30 minutes of using the device. Overall, 64 of the 73 patients (88 percent) transitioned to medication assisted therapy after five days using the device, along with any medications needed for persistent symptoms, such as nausea and vomiting.